Endocrine Abstracts

It has been hypothesized that prolactin may act on the immune system. It has been suggested that prolactin may act on the immune system and may be implicated in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, as mild hyperprolactinemia has been found in patients with systemic lupus erythematosus.We tested the hypothesis that prolactin may act on the immune system and induce the development of autoim...

Low vitamin D levels have been found in patients with diabetes mellitus type 2 and have been correlated with poor glycemic control. There are observations suggesting that vitamin D levels may be low in obesity.The aim was to study vitamin D levels in obese individuals.The levels of 25(OH)D3 were measured in 30 obese individuals aged 42.67 years (mean), range 27–64, BMI 35.49 (mean), range 30–46 and 37 control s...

Thyroid disease epidemiology has changed recently. This change may be related to changes in the iodine status of the environment. Iodine deficiency was observed in earlier years in Greece. The progression of multinodular goiter to hyperthyroidism was frequently observed. Nowadays, the development of autoimmune thyroiditis is frequently observed in patients with simple or nodular goiter. This development may be related to the proinflammatory action of iodine, iodine being nowad...

Vitamin D is synthesized in the skin. Low vitamin D levels have been observed in African Americans. However, the relationship between vitamin D and skin color has not been completely evaluated.The aim was to study the relationship between dark skin color and vitamin D levels in healthy individuals.Vitamin D (25(OH)D3) levels were measured in 15 dark skinned individuals. All subjects were immigrants, having migrated to Gr...

Nodular hyperplasia of the adrenal as a cause of Cushing’s syndrome is rare. Adrenal tumors, frequently causing syndromes such as hyperaldosteronism due to autonomous hormone secretion, have been described in patients with renal cysts. The aim was to describe the case of a female patient with diffuse adrenal hyperplasia, subclinical Cushing’s syndrome and renal cysts.A female patient aged 69 years presented with hyperplasia of the right adrenal...

HDR syndrome (hypoparathyroidism, deafness, renal dysplasia syndrome) is a rare clinical entity, which includes the simultaneous presence of hypoparathyroidism, sensorineural deafness and renal dysplasia. It is due to mutations of GATA3 gene in XP.10p and is inherited with the autosomal dominant type.The aim was to describe the case of a patient with clinical symptoms and laboratory and imaging findings compatible with HDR or Barakat syndrome.<p clas...

Adrenal rests, nodules of the adrenal, in patients with chronic elevation of ACTH levels have been previously described.The aim was to describe the case of a patient with an adrenal tumor and late onset 21-hydroxylase deficiency.A female patient, aged 76 years, presented with an incidentally discovered mass of the left adrenal measuring 1.2 cm. The patient was short with a height of 152 cm. Morning serum ACTH levels were 31 pg/ml, ...

Adrenal incidentalomas are increasingly recognized today as a result of technology use, such as computed tomography and magnetic resonance imaging. Adrenal incidentalomas are of diverse nature and their secretory activity is currently on research focus.The aim was to describe 39 consecutive patients with adrenal incidentalomas presenting over a period of 1 year.Materials and methods: A group of 39 consecutive patients with adrenal ...

Vitamin D deficiency is increasingly recognized today having taken the form of a modern epidemic. Vitamin D, being synthesized in the skin under the effect of ultraviolet light has been originally thought of as occurring only in areas of the world where people are not exposed to the sun. However, it has recently been observed that vitamin D deficiency exists even in sunny areas. Recent observations suggest that vitamin D deficiency is related to significant comorbidity, specif...

Male osteoporosis is a reality and in many cases appears to be secondary to drug administration. Many pharmaceutical agents are related to the appearance of osteoporosis, affecting bone metabolism by multiple and diverse mechanisms.The aim was to describe the case of a patient who presented with male osteoporosis of multiple drug aetiology.A patient, male aged 52 years, an orthodox priest, presented with spontaneous fractures and d...